📄 Category

public and global health

386 papers

Public and global health examines how we protect communities from disease, manage outbreaks, and improve well-being across the world. This vital field connects diverse research on everything from infectious disease control and vaccination strategies to the social factors that shape our collective health. Because these studies often impact policy and daily life, understanding them quickly is more important than ever.

At Gist.Science, we track every new preprint published in this category on medRxiv to ensure you never miss a breakthrough. We process each submission to provide both plain-language explanations for general readers and detailed technical summaries for experts, making complex findings accessible to everyone.

Below are the latest papers in public and global health, freshly summarized from the most recent medRxiv releases.

📄 public and global health

Standardized country-level delivery unit cost estimates for routine childhood, routine adolescent, and campaign vaccination: an updated modeling analysis

This study utilizes Bayesian meta-regression models on updated empirical data to generate standardized, country-level estimates of immunization delivery unit costs for routine childhood, routine adolescent, and campaign vaccination strategies across low- and middle-income countries, providing essential evidence for global vaccination planning and budgeting.

Portnoy, A., Clarke-Deelder, E., Holroyd, T. A., Hogan, D. R., Mengistu, T., Menzies, N. A.2026-03-17
📄 public and global health

Genomic characterization of the 2024/2025 Mpox outbreak in Uganda

This study characterizes the 2024/2025 Mpox outbreak in Uganda through genomic analysis of 511 samples, revealing substantial viral diversification, multiple cross-border introductions from the Democratic Republic of Congo, and the co-circulation of distinct lineages that underscore the critical need for integrated regional surveillance.

Kanyerezi, S., Ayitewala, A., Nsawotebba, A., Makoha, C., Tusabe, G., Kabahita, J. M., Oundo, H. R., Seruyange, J., Teny (…)2026-03-17
📄 public and global health

A Tale of Two Lenses: Emergency department indoor-air hybrid-capture metagenomics complements wastewater by adding a human-focused respiratory virus perspective

This study demonstrates that while wastewater surveillance offers broad, population-level viral diversity monitoring, emergency department indoor air sampling provides a complementary, human-focused perspective that yields higher-quality genomic data for characterizing respiratory viruses and detecting antiviral resistance.

Karatas, M., Gorissen, S., Swinnen, J., Geenen, C., Van Dyck, K., Cuypers, L., Tack, B., Hosten, E., Bloemen, M., Wollan (…)2026-03-15
📄 public and global health

Evaluating the Impact and Cost-Effectiveness of Typhoid Conjugate Vaccine Schedules Across Diverse Settings: A Multi-Model Comparison

A multi-model comparison commissioned by the WHO demonstrates that while routine typhoid conjugate vaccination at 9 months with a catch-up campaign and booster is generally the most impactful and cost-effective strategy, the optimal schedule ultimately depends on local incidence rates, case-fatality risks, and assumptions about vaccine waning.

Wenger, C. G. C., Grantz, K. H., Menkir, T. F., Muellenmeister, A. M., Pithawala, Z., Hutubessy, R., Mogasale, V., Kraay (…)2026-03-14
📄 public and global health

Evaluating the efficacy and cost-effectiveness of a digital, app-based intervention for depression (VMood) in community-based settings in Vietnam: A stepped-wedge cluster randomized controlled trial

This stepped-wedge cluster randomized controlled trial in Vietnam demonstrates that VMood, a digital app-based intervention for depression, significantly reduces depressive symptoms and is highly cost-effective, offering a scalable solution to address the treatment gap in low- and middle-income countries.

Chau, L. W., Yang, L., Krebs, E., Xie, H., Nguyen, V. C., Tran, H. N., Nguyen, T. T. X., Minas, H., Lam, R. W., Murphy (…)2026-03-14
📄 public and global health

Planning healthier cities by reframing the urban food landscape: measuring localised macronutrient exposure in Singapore

This study of Singapore demonstrates that localized saturated fat exposure, rather than fast food outlet density, is significantly associated with increased overweight risk, suggesting that urban planning in dense Southeast Asian cities should prioritize managing the macronutrient landscape to combat chronic disease.

Ma, P., Jin, S., Chew, Y. Z., Song, H., Dickens, B. L.2026-03-13
📄 public and global health

Implementing Community-Based Blood Pressure Groups in Zimbabwe - findings from process evaluation of a pilot intervention

A pilot study in Zimbabwe demonstrates that community-based blood pressure groups, facilitated by a combination of lay health workers and community champions, are a feasible and acceptable intervention that improves hypertension knowledge, medication adherence, and well-being among participants.

Mhino, F. M., Chingono, R. M. S., Chivandire, T., Sekanevana, C., Mpandaguta, C. E., Mwanza, T., Mutengerere, A., Ndanga (…)2026-03-13
📄 public and global health

Randomised controlled trial of social prescribing in schools to reduce loneliness in pupils (INACT): Trial study protocol

The INACT trial is a randomized controlled study evaluating the effectiveness and cost-effectiveness of a school-based social prescribing program compared to standard signposting in reducing loneliness and improving wellbeing among young people in England.

Hayes, D., Booth, R. J., Bu, F., Humphrey, N., Qualter, P., Sticpewich, L., Bone, J. K., Stuttard, H., Ellis, S., Maguir (…)2026-03-13
📄 public and global health

The Multiple Layers of Childhood Adversity and Premature Mortality: Synthesizing Life-course Data on Individual, Family and Neighborhood Adversity in 1.2 million individuals

This nationwide study of over 1.2 million individuals demonstrates that childhood adversity operates across multiple interconnected layers—individual, family, and neighborhood—where their co-occurrence and interaction, particularly between family and individual factors, significantly amplify the risk of premature mortality, highlighting the need for comprehensive, multi-layered interventions to address lifelong health inequalities.

Rod, N. H., Kaer Bennetsen, S., Elsenburg, L. K., Sabel, C., Taylor-Robinson, D., Kovacs, D., Zucco, A. G., de Vries, T. (…)2026-03-12